Scientist I/II

Ryvu Therapeutics is a clinical-stage drug discovery and development company focused on novel small molecule therapies that address emerging targets in oncology.

We are looking for team-oriented, independent biologist/ biotechnologist with strong background in mammalian cell culture and solid technical expertise (e.g. RNAi/CRISPR, flow cytometry, WB, qPCR) to strengthen our discovery development process. This position combines laboratory and conceptual work with full responsibility for the task assigned.

KEY RESPONSIBILITIES

• Laboratory-based position with 70% laboratory work and 30% of data analysis and conceptual work
• Establishing primary cell cultures
• Performing complex and technically challenging experiments (target identification using whole-genome CRISPR screenings, target validation studies and secondary functional pharmacology assays)
• Analyzing biological results and drawing conclusions, reporting in the format of Electronic Lab Notebooks
• Implementation of new research methods and protocols as part of current needs
• Proactively seeking out new information in the literature and incorporate this into individual projects as well as the overall program
• Independent work on the dedicated sub-projects
• Presenting research results and methodologies at weekly meetings with immediate supervisor and project leader, project team meetings and other research forums

• MSc degree in Molecular Biology, Biotechnology and 2+ years of experience in academia or industry or PhD degree
• Previous experience in the fields of cancer biology
• Experience in cell-based assay development in 2D and 3D models
• Technical expertise with mammalian cell culture and standard molecular biology techniques like ELISA, Western Blot, qPCR, flow cytometry as well as cytotoxicity, proliferation assays and assessing drug synergism
• Experience in working with cell-based assays in microplate format - medium throughput
• Practical experience with analysis software such as GraphPad Prism, Excel, FlowJo is strongly preferred
• Previous experience with primary cell cultures and in vitro activity determination of biological drugs, RNAi and/or CRISPR mediated knock-down techniques is a plus
• Analytical thinking approach, literature search skills, ability to work independently on a certain topic
• Willingness to learn and adopt new experimental techniques
• Good knowledge of written and spoken English

• Work in one of the most innovative companies in the region with a proven track record and high perspective of growth
  
• Collaborative and supportive work culture
  
• Training program enabling scientific development: Ryvu Academy, scientific lectures, participation in conferences
• Package of benefits: Luxmed, Multisport and many others
  
• Onsite support for foreigners and help with relocation
• Mindgram - wellbeing platform