Scientist - High Throughput Screening Expert
3 tygodni temu
About the Role
Selvita is a global integrated drug discovery partner for the pharmaceutical and biotechnology industries. We are seeking a highly motivated Scientist to join our Core Assay Development & Screening Unit within the Cell and Molecular Biology Department.
Key Responsibilities
- Design and construction of the HTS platform at Selvita
- Developing target-relevant biochemical and cell-based assays, including optimization, validation, and troubleshooting
- Evaluation of novel cell-based screening initiatives for implementation into the group portfolio
- Converting assays into HTS format, including assay miniaturization to 384-well / 1536-well format
- Design and implementation of key in vitro pharmacology experiments for low-throughput compound profiling
- Performing HT screens and hit identification
- Statistical analysis, reporting, and critical data evaluation for providing a scientific contribution to internal drug discovery projects
Requirements
- MSc in pharmacology, molecular biology, biotechnology, or similar discipline with minimum 2 years of experience in a biotech/pharma setting or Ph.D. in relevant biological sciences
- Good knowledge of in vitro pharmacology concepts, with a strong focus on at least one of the following areas: intracellular signaling, cancer metabolism, immunology, CNS
- Experience in working with cell lines and cell-based assays in microplate format
- Prior experience with mid-to-high throughput screening, liquid handling devices, and lab automation will be a plus
- Analytical and problem-solving skills, with proven troubleshooting experience
- Well-developed multi-tasking, flexibility, and team working skills
- Scientific presentation and interpersonal communication skills
- Fluency in English
About Selvita
Selvita is a stable employer with a clear perspective for the future. We offer extensive research facilities and modern laboratories, daily cooperation and know-how exchange with an experienced research team, long-term cooperation based on stable employment conditions and a clear career path, and support of experienced mentors with international scientific experience.
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