Scientist - High Content Screening
4 tygodni temu
Location
"> Kraków, Poland Offer descriptionSelvita is a global integrated drug discovery partner for the pharmaceutical and biotechnology industries with laboratories in Poland (Krakow & Poznan), Croatia (Zagreb), and offices in Cambridge, UK, Greater Boston Area & San Francisco Bay Area in the US. The company offers drug discovery support at every stage of the early discovery phase up to the preclinical research phase.
Continuous recruitment – that’s about Selvita We are focused on constant team growth and we hire new employees on an ongoing basis. The team growth rate correlates with the growth of the project portfolio we perform for our clients. We are a stable employer with a clear perspective for the future.
Due to constant development, currently, we are seeking a candidate for a Scientist position, to join the developing High Content Screening facility within a large project initially focused on assay development in the areas of neuroinflammation and fibrosis. We are seeking a self-motivated applicant with a strong interest in high-content experimentation and assay development for drug discovery. The person will have strong hands-on experience with mammalian cell culture (including some experience with hiPSC-derived cells), immunofluorescence/immunocytochemistry, standard molecular biology methods, direct knowledge of software for imaging analysis, and basic skills on new scripts generation for the development of innovative HCS phenotypic assays.
At Selvita, we work knowing that the research we do, makes an impact on human lives.
Region Kraków Key responsibilities Development of novel high-content assays for drug screening in a multi-task project. Growing cell cultures in ongoing projects. Execute medium to high-throughput assays for drug discovery and further compound pharmacological characterization. Work collaboratively with other scientists in particular for the generation of new scripts or analytical AI and Machine Learning-based methods for high content analysis. Execute, troubleshoot and communicate tasks independently and effectively. Perform data analysis and write reports on research findings, reporting directly to the project leader. Maintain extremely organized and accurate records. Provide regular feedback at inter-team meetings. Provide routine scientific reports. Your background MSc in Biology, Molecular Biosciences, Biotechnology or related disciplines with a minimum of four years of experience in an industrial environment (preferably Ph.D. in Biology, Molecular Biosciences, Molecular Cell Biology, Cellular and Molecular Pharmacology, or related scientific disciplines with a minimum of two years of experience in an academic post-doc or industrial environment). Strong experience with mammalian cell culture (experience with hiPSC/hESC and primary cells is highly desired). Immunofluorescence/Immunocytochemistry and imaging acquisition (in particular confocal imaging) strong experience and basic knowledge of FRET analysis. Experience with High Content Screening systems in a medium to high-throughput assay fashion with strong skills in cell-based assay development and validation with standard HTS/HCA parameters. Knowledge of large data transfer will be a plus. Knowledge of intracellular cell signaling and pathways characterization. Knowledge of the cellular mechanism of protein-to-protein interaction is desirable. Experience with standard molecular biology techniques - i.e. siRNA qPCR, and eventually Western blotting is a plus. Excellent written, verbal and interpersonal communication skills. Strong organizational skills and ability to prioritize a substantial workload. Good spoken and written English. Your benefits package Extensive research facilities and modern laboratories. Daily cooperation and know-how exchange with an experienced research team. Long-term cooperation based on stable employment conditions and a clear career path. Support of experienced mentors with international scientific experience. Benefits: private medical care, on-site fitness zone & subsidized sports card, lunch benefits & fruits in the office, on-site, subsidized kindergarten. Support in legalization and relocation from abroad. Language courses (English & Polish). Complex training programs. Support & incentive bonus for completing Ph.D. Various sports initiatives. Referral program.-
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