Postdoctoral Researchers in Laboratory of Neurodegeneration

2 tygodni temu

Warszawa, Mazovia, Polska Euraxess Pełny etat

International Institute of Molecular and Cell Biology in Warsaw

Organisation/Company International Institute of Molecular and Cell Biology in Warsaw Department Laboratory of Neurodegeneration Research Field Biological sciences » Biology Researcher Profile Recognised Researcher (R2) Country Poland Application Deadline 30 Jun :55 (Europe/Brussels) Type of Contract Temporary Job Status Full-time Hours Per Week 40 Offer Starting Date 1 Sep 2024 Is the job funded through the EU Research Framework Programme? Not funded by an EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Laboratory of Neurodegenerationat the International Institute of Molecular and Cell Biology (IIMCB) in Warsaw ( ), headed by Prof. Jacek Kuznicki is looking foraPostdoctoral Researcher.

You will join the projectentitled "How inactivation of mitochondrial calcium uniporter protects dopaminergic neurons", which is carried out as the OPUS grant 2023/49/B/NZ4/02744 of the Polish National Science Centre. The aim of this project is to identify ferroptosis associated genes that are turned on or off in LRRK2 and PINK1 Parkinson Disease models when MCU inactivation rescues dopaminergic neurons, and to understand the mechanism of protection. We will induce ferroptosis in zebrafish lines and dopaminergic neurons obtained from human iPSCs with PINK1 or LRRK2 mutations and characterize features of both types of models.

Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent

Skills/Qualifications

As a postdoctoral researcheryou will be responsible for characterization of ferroptosis in patient-derived dopaminergic neurons (DNs); identification of MCU-sensitive ferroptosis associated genes (FAGs) in DNs and characterization of human proteins encoded by MCU-sensitive FAGs.

Specific Requirements

Requirements for the candidate:

  • Holds a doctoral degree/Ph.D. in biology, biotechnology, medicine or related field.
  • Has excellent knowledge of molecular and cell biology.
  • Experience in cell culture, especially of iPSCs, will be of advantage.
  • Has expertise or shows strong interests in neurobiology, is motivated for experimental work, passion for science.
  • Gathered extensive experience in laboratory work, including microscopic techniques.
  • Has research achievements documented by publication record and conference presentations.
  • Shows readiness to learn new skills and take challenges, has ability to work independently and think analytically.
  • Has excellent communication and writing skills.
  • Mobility and research experience abroad will be of advantage but not mandatory.
Languages ENGLISH Level Good

Research Field Biological sciences » Biology Years of Research Experience 1 - 4

Additional Information

Weoffer:

  • Full employment contract for one year with the possibility of extension for up to 4 years.
  • Gross monthly remuneration approx. 8400 PLN (net approx. 6400 PLN) (the final monthly gross salary will be calculated individually during the employment process, considering the length of service). Additional bonuses such as Christmas bonus may supplement this salary.
  • Position with 100% focus on research (no teaching obligations).
  • Benefits including reduced rate for an individual medical care package and membership in MultiSport programme.
  • Full technical, administrative, and organizational support from professional English-speaking staff.
  • Participation in courses, scientific training, support from peers, and academic mentoring organized in-house, and at the EU-Life alliance institutes, MRC-HGU at the University of Edinburg and at the Flanders Institute of Biotechnology (VIB).
  • Work in a team of friendly researchers focused on excellent science.
Selection process

The ideal candidate should be able to pursue challenging tasks, think independently, achieve objectives, and collaborate with other researchers. Candidates will be selected in an open competition, according to the procedure complying with the rules of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers as a part of HR Excellence in Research strategy.

  • In the subject include"Postdoc OPUS_LN"and your first and last name.
  • Your application must be submitted in English and should contain a CV, a motivation letter, a description of your key achievements, and contact details at least two potential referees, including one of your supervisors.
  • Please include the following statement in your application:"I hereby agree to the processing of my personal data, included in the application documents by the International Institute of Molecular and Cell Biology in Warsaw, 4 Księcia Trojdena Street, Warsaw, for the purpose of carrying out thecurrent recruitment process."Your personal data will be processed for the purpose of the recruitment procedure by the International Institute of Molecular and Cell Biology in Warsaw. Full information is available under the
  • The competition may be extended until a suitable candidate is found.
Number of offers available 1 Company/Institute International Institute of Molecular and Cell Biology in Warsaw Country Poland City Warsaw Postal Code Street ks. Trojdena 2 Geofield
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